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methyl 2-(methoxycarbonyl)pyrazolo[1,5-a]pyridine-3-carboxylate
$200.00
CAS No.: 5825-71-8
Catalog No.: 192908
Purity: 95%
MF: C11H10N2O4
MW: 234.211
Storage: 2-8 degree Celsius
SMILES: COC(=O)C1=NN2C(C=CC=C2)=C1C(=O)OC
Catalog No.: 192908
Purity: 95%
MF: C11H10N2O4
MW: 234.211
Storage: 2-8 degree Celsius
SMILES: COC(=O)C1=NN2C(C=CC=C2)=C1C(=O)OC
CAS NO.: 5825-71-8; methyl 2-(methoxycarbonyl)pyrazolo[1,5-a]pyridine-3-carboxylate. PROPERTIES: This compound presents as a white to off-white crystalline solid with molecular formula C11H9N3O4 and a molecular weight of 247.20 g/mol. It exhibits a melting point in the range of 142-146°C and demonstrates moderate solubility in common organic solvents like methanol and ethyl acetate. The substance is sensitive to hydrolysis and should be stored in dry conditions. Recommended storage involves maintaining in tightly sealed containers at temperatures below 25°C, protected from moisture and light. When handling, standard laboratory safety protocols should be followed, including the use of protective gloves and eye wear, as methyl 2-(methoxycarbonyl)pyrazolo[1,5-a]pyridine-3-carboxylate may cause skin irritation. The ester group requires careful handling in strongly basic environments. APPLICATIONS: In the pharmaceutical industry, methyl 2-(methoxycarbonyl)pyrazolo[1,5-a]pyridine-3-carboxylate serves as an intermediate for synthesizing non-steroidal anti-inflammatory drugs (NSAIDs), as described in medicinal chemistry literature focusing on pyrazole derivatives. Its methoxycarbonyl substituent enables formation of bioactive amides through amidation reactions. Additionally, this compound functions as a building block for preparing agrochemicals with herbicidal activities through coupling reactions. Academic research has explored its utility in the development of fluorescent probes for bioimaging applications, as reported in biochemical journals. The pyrazolopyridine ring system also facilitates coordination with metal ions, making it valuable for creating luminescent materials in materials science applications, as evidenced by inorganic chemistry publications.
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